About StackBuilder
StackBuilder is a research-backed tool that helps you find the most effective peptides and supplements for your health goals, ranked by scientific evidence and optimized for your budget.
Our Mission
The supplement industry is plagued by marketing hype and pseudoscience. We built StackBuilder to cut through the noise. We analyzed over 45,000 scientific studies from PubMed to evaluate 195+ compounds across 18 health goals. Every compound in our database is scored using a rigorous 5-tier evidence system based on this published peer-reviewed research.
How Our Evidence System Works
Each compound is evaluated for each of the 18 health goals it may support. Our scoring considers:
- Study type and quality — Meta-analyses and RCTs carry more weight than animal studies
- Sample size and replication — Results confirmed across multiple studies score higher
- Effect size — Statistically significant doesn't always mean clinically meaningful
- Recency — Recent research is weighted more heavily
- Publication quality — Studies from respected journals rank higher
The 5-Tier System
Early-stage research, primarily in-vitro or very limited animal data.
Promising animal studies with plausible mechanisms, but limited human data.
Some human clinical trials with positive results, but more research needed.
Multiple well-designed human RCTs with consistent, clinically meaningful results.
Confirmed by meta-analyses and systematic reviews. Gold-standard evidence.
Important Note
StackBuilder is an educational tool, not a substitute for medical advice. Always consult with a qualified healthcare professional before starting any supplement or peptide regimen. See our full disclaimer.